Indication: Stroke risk in sickle cell disease; cerebral vasospasm (post-SAH); intracranial stenosis; right-to-left shunt detection; brain death confirmation
Patient supine. Use sector/phased array probe (2 MHz TCD probe preferred) set to low MI.
Transtemporal window: place probe at the temporal squama above the zygomatic arch. Identify the MCA at 45–65mm depth — it flows toward the probe (positive).
Identify ACA at 60–80mm (flows away, negative). PCA at 60–70mm (flow direction varies by segment).
Record PSV, EDV, and mean velocity at each vessel. Calculate Lindegaard Ratio = MCA mean / ICA mean (>3 = vasospasm).
Transorbital window: REDUCE power to minimum MI. Place probe on closed eyelid. Ophthalmic artery at 40–50mm — normally toward probe.
Suboccipital window: patient flexes neck. Probe at foramen magnum. Basilar at 80–120mm (away from probe); vertebrals at 40–70mm.
For PFO: inject agitated saline IV during Valsalva. Count HITS (microembolic signals) within 25 cardiac cycles on MCA.
Vasospasm: MCA PSV >120 cm/s + Lindegaard Ratio >3. For PFO detection, inject agitated saline during Valsalva and count HITS within 25 cardiac cycles.
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